7/31/2023 0 Comments Umbilical artery dopplerWe were interested in how often this occurred in women who had a singleton, low-risk pregnancy (i.e. In this review, we aimed to determine how often pregnant women experience abnormal umbilical flow during pregnancy, in particular the occurrence of absent or reversed flow. If the flow is absent or reversed, the baby may die. Poor umbilical blood flow can lead to a baby experiencing growth restriction. When this blood flow is restricted, absent or even reversed, the health of the baby can be threatened. There are insufficient data from lower-income countries and further research is required.ĭoppler ultrasound can be used during pregnancy to determine how well blood is flowing through the umbilical cord. ConclusionsĮvidence from largely observational studies in higher-income countries suggests that AEDF and REDF are rare among low- and unselected-risk pregnant women. There was limited evidence from low- and middle-income countries. Four of these studies were in unselected-risk women and five were conducted in high-income countries. However, 55 AEDF or REDF cases were identified from just six studies (prevalence 0.08% to 2.13%). Thirty-six studies reported zero AEDF or REDF cases. ResultsĪ total of 42 studies (18,282 women) were included. Two authors assessed eligibility and extracted data on primary (AEDF and REDF) and secondary (fetal, perinatal, and neonatal mortality, caesarean section) outcomes, with results presented descriptively. All randomized or non-randomized studies reporting AEDF or REDF prevalence based on Doppler assessment of umbilical arterial flow > 20 weeks’ gestation were eligible. We searched PubMed, Embase, CINAHL, CENTRAL and Global Index Medicus with no date, setting or language restrictions. In this systematic review, we aimed to synthesise available data on the prevalence of AEDF or REDF. This may be related to fewer events of abnormal Doppler flow, however the prevalence of absent or reversed end diastolic flow (AEDF or REDF) in such women is unknown. While Doppler ultrasound screening is beneficial for women with high-risk pregnancies, there is insufficient evidence on its benefits and harms in low- and unselected-risk pregnancies.
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